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Modules Page
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Modules Page


Meet our 2025 Key Opinion Leaders
Sana Al-Khatib
Professor of Medicine at Duke University | Cardiac Electrophysiologist
Duke University
Emeka Anyanwu
Non-Invasive Cardiologist and Echocardiographer | Director, Center for Cardiovascular Informatics | Clinical Informatics Manager
University of Pennsylvania School of Medicine | Penn Medicine Center for Health Care Innovation
Tina Baykaner
Assistant Professor
Department of Internal Medicine | Division of Cardiovascular Medicine and Electrophysiology | Stanford University
Sumeet Chugh
Price Endowed Professor & Associate Director, Heart Institute | Director Artificial Intelligence in Medicine
Cedars-Sinai Health System
Daniel Cooper
Professor of Medicine | Director of the Clinical Cardiac Electrophysiology Fellowship
Washington University School of Medicine
Brynn Dechert-Crooks
Pediatric Electrophysiology Nurse Practitioner
University of Michigan Congenital Heart Center
Isabel Deisenhofer
Head, Department of Electrophysiology
German Heart Center Munich Department of Electrophysiology
Thomas Deneke
Cardiac Electrophysiologist
Clinic for Arrhythmology, University Heart Center Nuremberg, Paracelsus Medical University
Mehak Dhande
Interventional Cardiac Electrophysiologist | Physician Scientist
University of Pittsburgh Medical Center
Luigi Di Biase
Clinical Cardiac Electrophysiology
Albert Einstein College of Medicine at Montefiore Health System
Martha G. Ferrara
Family Nurse Practitioner | Assistant Director EP Services
White Plains Hospital-Montefiore Health Systems
Aileen Ferrick
Assistant Director of Cardiac Electrophysiology Research | Acute Care Nurse Practitioner
White Plains Hospital
Hamid Ghanbari
Vice Chair of Innovation, Assistant Professor & Cardiac Electrophysiologist
University of Michigan Cardiovascular Center
Janet K. Han
Associate Professor of Medicine | Cardiac Electrophysiology
UCLA | VA Greater Los Angeles Healthcare System / UCLA | Digital Health & Virtual Care
Jeroen Hendriks
Professor of Cardiovascular Nursing
Centre for Heart Rhythm Disorders, University of Adelaide
Arun Jose
Deputy Director & Head
BRIDGE Centre for Digital Health, Centre for Chronic Disease Control
Rodolphe Katra
Global Chief Artificial Intelligence (AI) Officer and a Technical Fellow
Consilium BioMedical
Anne Kroman
Associate Professor of Cardiac Electrophysiology | Director of the Lead Management Program, the Cardiac Device Clinic, and MUSC Heart Station
Medical University of South Carolina
David McManus
Richard M. Haidack Professor and Chair of the Department of Medicine
University of Massachusetts Chan Medical School
Nishaki Mehta
Associate Professor of Medicine
William Beaumont Oakland University School of Medicine
George Stuart Mendenhall
Cardiac Electrophysiologist and Researcher | Chief Medical Officer
Scripps Memorial Hospital | Everbeat
Faisal Merchant
Director of Cardiac Electrophysiology and Associate Professor of Medicine
Emory Healthcare
Jessica Mullenix
Cardiac Electrophysiology Nurse Practitioner
U.S. Department of Veterans Affairs Cardiology Office
Devi Nair
Director of the Cardiac Electrophysiology & Research
St. Bernards Medical Center & Arrhythmia Research Group
Sanjiv Narayan
Professor of Medicine | Director of the NIH T32 Computational Medicine Training Program (CHIP) | Co-Director of the Arrhythmia Center
Stanford University
Ken Nelson
Partner | Board Chairman & Investor | Investor & Mentor
Medtech Advantage Fund | CardiaCare | HeartBeam, BloomLife, & HeartX
Jose Osorio
Medical Director of Electrophysiology – HCA Florida Miami | Founder and CMO | Founder and President
HCA Florida Miami | 3PH Alliance | Heart Rhythm Clinical Research Solutions
Deepak Padmanabhan
Assistant Professor
Sri Jayadeva Institute of Cardiovascular Sciences and Research
Ambarish Pandey
Associate Professor of Cardiology in Internal Medicine
University of Texas Southwestern Medical Center
Rod Passman
Jules Reingold Professor of Electrophysiology & Cardiac Electrophysiologist
Northwestern University Feinberg School of Medicine
Jeanne Poole
Cardiac Electrophysiologist | Director | Professor of Cardiology and Medicine
University of Washington Medical Center and School of Medicine
Lisa Roelle
Pediatric Electrophysiology Physician Assistant
Washington University in St. Louis & St. Louis Children’s Hospital
Lauren Rousseau
Physician Assistant in the Section of Clinical Cardiac Electrophysiology
Brigham and Women’s Hospital
Andrea Russo
Academic Chief, Division of Cardiology | Director, Cardiac Electrophysiology and Arrhythmia Services | Director, CCEP Fellowship
Cooper University Hospital
Prashanthan Sanders
Cardiac Electrophysiologist & Director of Cardiac Electrophysiology
University of Adelaide
Samuel F. Sears
Professor in the Departments of Psychology and Cardiovascular Sciences | Division Chief of Innovation and Research | Associate Director of the ECU Cardiology Fellowship
East Carolina Heart Institute
Kalyanam Shivkumar
Professor & Director, Center for Interventional Programs
UCLA Health System, UCLA Cardiac Arrhythmia Center & EP Programs
Jennifer Silva
Director Pediatric Electrophysiology | Washington University SOM
Washington University SOM
Jagmeet Singh
Professor of Medicine | Cardiac Electrophysiologist & Founding Director of the Resynchronization and Advanced Cardiac Therapeutics Program
Harvard Medical School | Massachusetts General Hospital Heart Center
Konstantinos Siontis
Cardiac Electrophysiologist | Assistant Professor of Medicine at Mayo Clinic | Director of the Cardiac Radioablation
Mayo Clinic
Yekaterina Spivak
Physician Assistant | Inventor & Founder
Children’s Hospital of Philadelphia | Laally
Uma Srivatsa
Senior Cardiac Electrophysiologist | Professor and Director of Arrhythmia Services
University of California – Davis
Kamala Tamirisa
Clinical Cardiac Electrophysiologist & Cardiac MR Imaging Specialist
Texas Cardiac Arrhythmia
Kevin Thomas
Vice Dean for Equity, Diversity and Inclusion | Professor of Medicine, Cardiac Electrophysiologist, Health Disparities Researcher
Duke University Health System
John Triedman
Professor of Pediatrics | Former Chief of Pediatric EP
Harvard Medical School | Boston Children’s Hospital
Mintu Turakhia
Chief Medical and Scientific Officer + EVP, Product Management and Innovation | Professor of Medicine and Cardiac Electrophysiologist
iRhythm Technologies, Inc. | Stanford University
Paul Varosy
VA Eastern Colorado Health Care System | University of Colorado School of Medicine | Veterans Health Administration Cardiology
Nicholas Von Bergen
Professor of Pediatrics in Pediatric Cardiac Electrophysiologist | Co-Founder
University of Wisconsin-Madison | Atrility Medical, LLC
Elaine Wan
Esther Aboodi Associate Professor of Medicine in Cardiology and Cardiac Electrophysiology | Attending Physician at New York-Presbyterian Hospital
Columbia University Medical Center, College of Physicians and Surgeons | New York-Presbyterian Hospital
Ramsey Wehbe
Heart Failure Cardiologist & Assistant Professor of Medicine
Medical University of South Carolina in Charleston
J. Peter Weiss
Cardiac Electrophysiologist
Banner University of Arizona Medical Center Phoenix (BUMCP)
Rebecca Yapejian
CRM Senior Field Clinical Representative | Cardiac Electrophysiology Nurse Practitioner | Former Software Engineer
Boston Scientific | DOCS Health Careers
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Programs-at-a-Glance
Events
September 04, 2025
08:00 AM (EDT)
– 08:50 AM (EDT)
Innovation Summit Section l: Innovation in Cardiac Mapping
Innovation Summit Section l: Innovation in Cardiac Mapping
Jonathan Piccini | Shlomo Shpun | Sabine Ernst | Vadim Federov | Philip Haeusser | Mélèze Hocini | Jerome Kalifa | Devi Nair | Sanjiv Narayan
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
08:55 AM (EDT)
– 09:45 AM (EDT)
Innovation Summit Section ll: Innovation in Cardiac Ablation
Innovation Summit Section ll: Innovation in Cardiac Ablation
Devi Nair | Melanie Gunawardene | Sabine Ernst | H. Immo Lehmann | Vivek Y. Reddy | Andrea Sarkozy | Kalyanam Shivkumar
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
10:00 AM (EDT)
– 10:50 AM (EDT)
Innovation Summit Section III: Pacing & Implanted Device Therapy
Innovation Summit Section III: Pacing & Implanted Device Therapy
Emily Zeitler | Ulrika Birgersdotter-Green | Mikhael El-Chami | Avi Fischer | Devi Nair | Venkatakrishna Tholakanahalli | Niraj Varma
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
10:50 AM (EDT)
– 12:00 PM (EDT)
Innovation Summit Section IV: Diagnosis, Risk Stratification & Treatment of Arrhythmias
Innovation Summit Section IV: Diagnosis, Risk Stratification & Treatment of Arrhythmias
Elaine Wan | Patrick Boyle | Jennifer N. Avari Silva | Yaariv Khaykin | Zak Loring | Steven Lubitz | Devi Nair | Sotirios Nedios | Jagmeet Singh
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
01:00 PM (EDT)
– 01:45 PM (EDT)
From Spark to Scale: Building a Culture of Innovation in MedTech
From Spark to Scale: Building a Culture of Innovation in MedTech
Kris Shah | Suneet Mittal
Kris Shah, former President of Baylis Medical and a driving force behind one of Canada’s most influential MedTech success stories, joins Dr. Suneet Mittal for a main tent conversation at HRX 2025. Together, they will explore how innovation can be intentionally cultivated—from early-stage ideation to global scale. Drawing from his leadership at Baylis Medical, Kris will share how he created an environment that empowered engineers and clinicians to challenge convention, embraced failure as a learning tool, and ultimately brought disruptive cardiovascular technologies to market. Attendees will gain insight into the strategic, cultural, and operational levers needed to sustain innovation in a highly regulated, risk-averse industry. Whether you’re a founder, physician, or executive, this session offers a blueprint for how to lead boldly and innovate with purpose.
02:00 PM (EDT)
– 02:45 PM (EDT)
AFib, AI, and the Future of Care: Revolution or Just Hype?
AFib, AI, and the Future of Care: Revolution or Just Hype?
Mintu Turakhia | Jeffrey Wessler
This session explores how AI-driven innovations are transforming atrial fibrillation (AF) management, from prevention to long-term care. Experts will discuss AI-powered digital education, solutions for early intervention, and technology’s role in addressing key risk factors like obesity, sleep apnea, and exercise. Is AI the game-changer in achieving sustainable AF care, or just another trend? Join us to find out.
02:00 PM (EDT)
– 02:45 PM (EDT)
Innovation Partner Roundtable – Continued Opportunities for Innovation in the Era of PFA – Powered by Kardium
Innovation Partner Roundtable – Continued Opportunities for Innovation in the Era of PFA – Powered by Kardium
As Pulsed Field Ablation (PFA) transitions from investigational to early commercial use, electrophysiology teams are reimagining workflows, tools, and treatment strategies. This expert roundtable will examine how early adopters are integrating PFA into clinical practice—from evolving lesion strategies and HD mapping techniques to contact sensing and directional energy delivery. Panelists will share first-hand insights on optimizing lesion durability, minimizing collateral damage, and tailoring ablation approaches for complex anatomies. With an eye toward next-generation technologies currently under evaluation, the discussion will also explore the innovations shaping the future of PFA and what’s needed to support continued progress in safety and efficacy.
02:00 PM (EDT)
– 02:45 PM (EDT)
Remote Monitoring and Data Management: Challenges and Innovations
Remote Monitoring and Data Management: Challenges and Innovations
Aileen Ferrick | Jessica Mullenix | Carissa Pistilli | Yekaterina Spivak | Julie Thomas | Amy Tucker | Rebecca Yapejian
In this session, we will delve into the evolving landscape of remote monitoring, addressing the increasing challenges associated with managing vast amounts of data collected from wearables, implantables, and external monitoring devices. We will explore the complexities of integrating data across diverse platforms, with a particular focus on overcoming interoperability barriers.
02:45 PM (EDT)
– 03:30 PM (EDT)
Pediatric EP and Cardiac Tech: Lifesaver or Just the Start?
Pediatric EP and Cardiac Tech: Lifesaver or Just the Start?
Brynn Dechert-Crooks | Benjamin Hale | Jamie Harris | Lisa Roelle | Nicholas Von Bergen
From life-changing interventions to emotional uncertainties, how does cardiac technology shape the journey of children and young adults with arrhythmias? This session explores the evolving role of electrophysiology (EP) in pediatrics, the impact of cutting-edge devices, and the patient experience—balancing fear, hope, and the promise of innovation. Are we maximizing technology’s potential, or is is there more to uncover in improving outcomes and quality of life for young patients?
02:45 PM (EDT)
– 03:30 PM (EDT)
HRX Roundtable – Non-Watch Wearables in Cardiovascular Care
HRX Roundtable – Non-Watch Wearables in Cardiovascular Care
Marco Perez | Arik Ben Ishay | Derek Exner | Yaariv Kahykin
From smart rings and adhesive patches to smart clothing and implantables, non-watch wearables are reshaping how we monitor, diagnose, and manage cardiovascular disease outside traditional clinical settings. This roundtable will explore the expanding landscape of non-watch wearable technologies, their clinical utility in arrhythmia detection, heart failure monitoring, and vital sign assessment, and the challenges of data validation, workflow integration, and reimbursement. Panelists will share insights on current use cases, patient engagement strategies, and the future promise of these emerging tools in delivering continuous, personalized cardiovascular care.
02:45 PM (EDT)
– 03:30 PM (EDT)
Sudden Cardiac Arrest Session
Sudden Cardiac Arrest Session
Mina K. Chung | Alan Cheng | Sumeet Chugh | Richard Price | Monique Starks | Jake Sunshine
SCA is a persistent public health problem, but little has changed over the past several decades. This session will highlight new approaches to the prevention and treatment of SCA that leverage innovative technologies and systems of care. Special attention will be given to how different technologies, education, and predictive analytics can synergize to improve the problem of SCA and improve outcomes.
03:45 PM (EDT)
– 04:30 PM (EDT)
Personalized Care Through Digital Twins – Foundational or Fantasy?
Personalized Care Through Digital Twins – Foundational or Fantasy?
Natalia Trayanova | Patrick Boyle | Jonathan Chrispin | Tanmay Gokhale | Liat Tsoref
Digital twins offer the promise to develop, test, and validate potential personalized solutions for heart rhythm care that are unique to a given individual and their myocardial substrate. Early studies have been promising. However, there are significant challenges from several different areas including operational, computational, and efficacy. This session will engage in discussing whether digital twins will become a foundational core of EP care or remain a fantasy.
03:45 PM (EDT)
– 04:30 PM (EDT)
Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
Dominic Abrams | Vassilios Bezzerides | Gabriel Brooks | Samuel Hall | Cain McClary
Inherited arrhythmia syndromes and cardiomyopathies pose a significant clinic challenge, with suboptimal treatment and a large unmet need. Over the last decade several new therapies have been developed which target the underlying genetic and molecular causes of these conditions, and many are progressing from pre-clinical research to clinical trials. These discoveries offer a potential paradigm shift in treatment strategies and quality of life for patients. This panel focused on novel genetic and molecular therapies for inherited arrhythmia syndromes and arrhythmogenic cardiomyopathies will bring together experts with a broad range of experience including venture capital, clinicians, translational scientists, and biotech. The session will address a wide range of topics from lab discovery to commercialization.
03:45 PM (EDT)
– 04:30 PM (EDT)
HRX Roundtable – Using Large Language Models in Clinical Practice
HRX Roundtable – Using Large Language Models in Clinical Practice
Hamid Ghanbari | Jacqueline Shreibati
Large Language Models (LLMs) are rapidly moving from experimental tools to real-world clinical assistants. This roundtable explores how LLMs are being integrated into everyday workflows across cardiology and beyond—powering clinical documentation, decision support, patient communication, and medical education. Panelists will discuss emerging use cases, real-world implementation challenges, and ethical considerations such as bias, data privacy, and regulatory oversight. Join us for a pragmatic, frontline view of how AI is reshaping the clinician-patient interface and what it will take to move from promise to practice.
03:45 PM (EDT)
– 04:30 PM (EDT)
Top 5 AbstracX
Top 5 AbstracX
Daniel Morin (Moderator) | Yaariv Khaykin | Bobak Mosadegh | Nobunari Tomura | Bryant Wyatt
The Top 5 scoring AbstracX Researchers will share their research.
03:45 PM (EDT)
– 04:30 PM (EDT)
Innovation Partner Roundtable: Potential of AI to Improve CIED Remote Monitoring – Powered by 91Life
Innovation Partner Roundtable: Potential of AI to Improve CIED Remote Monitoring – Powered by 91Life
Prashanthan Sanders | Meghan Reading Turchioe | Niraj Varma
This session will explore the opportunity for AI to assist with assessment of device interrogations, arrhythmia detection and identification, alert management and generation of clinical synopsis to enhance efficiency of CIED remote monitoring. The session will also explore how AI can enhance “population level” understanding of a large CIED remote monitoring program.
04:30 PM (EDT)
– 05:15 PM (EDT)
Evolution, Integration, and Disruption of Ultrasound Technologies in the EP Laboratory
Evolution, Integration, and Disruption of Ultrasound Technologies in the EP Laboratory
Amin Al-Ahmad | Luigi Di Biase | Christoph Hennersperger
There is an unprecedented surge in innovation surrounding intracardiac ultrasound and its integration into electrophysiologic care. Future iterations of 4-D intracardiac ultrasound, next-generation integration into mapping systems, and the use of ultrasound for therapeutic purposes all have the potential to significantly change practice. This session will review these key innovations and how they may improve care in the EP laboratory.
04:30 PM (EDT)
– 05:15 PM (EDT)
HRX Roundtable – Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
HRX Roundtable – Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
Gabriel Brooks | Vassillios Bezzerides | David Milan | Samuel F. Sears
Current treatments for inherited arrhythmias focus on medical therapy and cardiac implanted electronic devices. While they suppress arrhythmias and prevent fatal sequelae they do not address the fundamental underlying cause of the disease. While gene therapy has been a theoretical solution to fix the underlying cause of inherited arrhythmias, recent innovations are finally bringing these therapies closer to clinical care. This session will explore the different genetic therapies in development for a variety of disorders and how they will impact persons with inherited arrhythmias from a clinical and psychological standpoint.
04:30 PM (EDT)
– 05:15 PM (EDT)
HRX Roundtable – Innovation in PPG Technology
HRX Roundtable – Innovation in PPG Technology
Dominik K Linz | Lars Grieten | Nassir Marrouche | Yosef Safi Harb | Emma Svennberg
PPG has rapidly evolved from a consumer wellness tool into a promising clinical modality with wide-ranging applications in cardiovascular care. This roundtable will explore cutting-edge innovations in PPG technology and how it is being deployed to transform detection, diagnosis, and disease management. From arrhythmia monitoring to blood pressure estimation, sleep apnea screening, and heart failure assessment, PPG-based tools are reshaping how and where care is delivered—especially when integrated into wearables, smartphones, and remote monitoring platforms. Experts from digital health startups, academic research, and clinical practice will examine key advances in signal processing, AI-enhanced analytics, and device miniaturization. We’ll also tackle the regulatory, validation, and clinical integration challenges that must be addressed to move from promise to practice.
04:30 PM (EDT)
– 05:15 PM (EDT)
Clinical Workflow: Interoperability, Decision-Making, and Solutions – What’s the Missing Link?
Clinical Workflow: Interoperability, Decision-Making, and Solutions – What’s the Missing Link?
David Slotwiner
This session explores how AI integration, EMR advancements, and remote monitoring can enhance physician decision-making, streamline workflows, and improve patient care. Panelists will discuss the impact of AI on billing and physician hours, the role of device-driven insights in heart failure management, and how RNs and APPs contribute to effective communication and data management. Join us for an insightful discussion on leveraging technology to optimize clinical efficiency and patient outcomes.
04:30 PM (EDT)
– 05:15 PM (EDT)
AI at the Point of Care: Redesigning Documentation for Clinicians
AI at the Point of Care: Redesigning Documentation for Clinicians
Dhanunjaya R. Lakkireddy
From dictation software to full-blown natural language processing assistants, AI-based documentation tools promise to free clinicians from the tedium of charting. Physician burnout is on the rise—can AI-driven documentation help turn the tide? Strategies for successful change management, physician buy-in, and ongoing system optimization will be highlighted. How do we ensure data accuracy, privacy, and seamless integration into diverse electronic health records? Panelists will discuss the practical implementation of AI-assisted documentation and patient communication, while maintaining patient-centered care.
05:30 PM (EDT)
– 06:30 PM (EDT)
AbstracX Happy Hour Session I – Powered by 91Life
AbstracX Happy Hour Session I – Powered by 91Life
Siddharth Agarwal | Leart Ajvazaj | Myrte Bartheis | Wen-Han Cheng | Mithilesh Das | Marye Gleva | Masahiro Makino | Nicolle Milstein | Geoffroy Napon | Ajay Tripuraneni
This engaging AbstracX Happy Hour session, powered by 91Life, kicks off with opening remarks from 91Life. Following the introduction, AbstracX presenters will present their work in a lively, informal setting designed to foster connection and conversation.
September 05, 2025
08:45 AM (EDT)
– 09:30 AM (EDT)
Main Tent Session Featuring Doron Harlev
Main Tent Session Featuring Doron Harlev
Doron Harlev | Jonathan Piccini
09:45 AM (EDT)
– 10:30 AM (EDT)
HRX AP Shark Tank: Fueling Innovation, Advancing Patient Care
HRX AP Shark Tank: Fueling Innovation, Advancing Patient Care
The HRX AP Shark Tank is an electrifying competition where allied professionals present groundbreaking ideas that have the potential to revolutionize patient care and advance electrophysiology practice. This event provides a unique platform for APs to pitch their most innovative research concepts, workflow enhancements, or practice-changing solutions to a panel of expert “sharks.”
How It Works:
– Top 5 Finalists: Authors of the five top‐rated submissions will be invited to present their ideas in person at HRX 2025.
– Expert Mentorship: Finalists will receive mentorship prior to their presentation to refine their ideas and maximize their impact.
– Live Pitch Session: Finalists will pitch their ideas live at HRX 2025 to a panel “sharks” comprised of industry leaders and EP experts.
– Winner Recognition: The most compelling idea will be awarded top honors, gaining visibility and credibility within the AP and EP communities.
09:45 AM (EDT)
– 10:30 AM (EDT)
Innovations in Autonomic Therapies for Atrial Fibrillation
Innovations in Autonomic Therapies for Atrial Fibrillation
Jonathan Piccini | Shih-Ann Chen | Marat Fudim | Stavros Stavrakis | Kalyanam Shivkumar
The autonomic nervous system is known to play a critical role in the initiation and/or triggering of many arrhythmias, including atrial fibrillation. Autonomic therapies have moved well-beyond isolated ablation of cardiac ganglionated plexi. This session will review the innovations that have expanded autonomic therapies, including tragus stimulation, renal sympathetic denervation, and future innovations for additional interventions.
09:45 AM (EDT)
– 10:30 AM (EDT)
Are Digital Innovations Accelerating Advances in Gene Therapy?
Are Digital Innovations Accelerating Advances in Gene Therapy?
With gene therapy advancing rapidly, how do digital innovations accelerate its impact on cardiovascular disease? This session explores the evolution of gene therapy trials, cutting-edge breakthroughs, and the role of AI, big data, and digital platforms in research, patient monitoring, and treatment optimization. Hear from experts and patient advocates as we examine whether technology is the key to making gene therapy more accessible, efficient, and transformative. Are we on the verge of a revolution, or just scratching the surface?
10:30 AM (EDT)
– 11:15 AM (EDT)
The Permanent Pacing of Tomorrow
The Permanent Pacing of Tomorrow
Mikhael El-Chami | Neal Bhatia | Janet K. Han | Anne Kroman | Kathryn Hilpisch
This session will detail the possibilities, potential technologies, and likely pathways for permanent pacing in the future. Specifically, this session will explore next generation pacing technologies, including but not limited to advances in leadless pacing, micro-devices, new epicardial pacing interventions, pacing for HFpE, and physiologic atrial pacing.
10:30 AM (EDT)
– 11:15 AM (EDT)
Innovation Partner Roundtable – Rethinking Rhythm Care: Technology-Driven Trends in ECG Monitoring Reshaping EP Practice – Powered by iRhythm
Innovation Partner Roundtable – Rethinking Rhythm Care: Technology-Driven Trends in ECG Monitoring Reshaping EP Practice – Powered by iRhythm
Suneet Mittal | Joshua Lampert
This roundtable will examine how long-term continuous ECG monitoring, remote diagnostics, and AI-assisted interpretation are enabling more accurate arrhythmia detection and more confident clinical decisions. We’ll discuss key applications including the ability to scan large streams of recorded data, AF and PVC burden assessment, ablation follow-up, and early identification of overlooked arrhythmias through the lens of what’s next for EPs in a digital-first world. We’ll discuss different AI approaches (high sensitivity, high specificity, multiple layers) and the technicians-in-the-loop versus fully autonomous AI. We’ll what’s next for ambulatory ECG AI, including LV dysfunction, sleep apnea, structural heart disease, and even hospitalization and health care utilization.
12:30 PM (EDT)
– 01:15 PM (EDT)
Heart Rhythm Innovation Morbidity and Mortality Conference – Avoiding Fatal Pitfalls
Heart Rhythm Innovation Morbidity and Mortality Conference – Avoiding Fatal Pitfalls
Avi Fischer | Daniel Cantillon | Jennifer N. Avari Silva
Not all innovation is successful. Many potential innovations fail in the pre-clinical or early testing phases – often for common reasons. This session will discuss the potential pitfalls in device development and how innovators can navigate these challenges with greater confidence by avoiding mistakes and missteps. The panel will discuss their “dream” innovations that didn’t come to fruition – and what they learned.
12:30 PM (EDT)
– 01:15 PM (EDT)
HRX Roundtable – Registries & Data Collection of the Future – New Ways to Learn
HRX Roundtable – Registries & Data Collection of the Future – New Ways to Learn
Sana Al-Khatib | Luigi Di Biase | Paul Varosy | Emily Zeitler
As digital innovation reshapes the electrophysiology landscape, the way we collect and learn from clinical data must evolve in parallel. This forward-looking roundtable will explore next-generation registries and data platforms designed to reduce abstraction burden, enhance clinical insights, and accelerate quality improvement across diverse practice settings. With the Heart Rhythm Society’s newly announced PFA Data Entry Platform—a clinician-led, AI-enhanced alternative to traditional registries—as a central case study, panelists will discuss how emerging models can modernize data collection for novel technologies like Pulsed Field Ablation. We’ll examine core design elements such as longitudinal tracking, integrated data sources, standardized APIs, and real-time benchmarking tools that support both clinical care and research.
12:30 PM (EDT)
– 01:15 PM (EDT)
Imaging 2.0: Multi-Modal Insights for Complex EP Cases
Imaging 2.0: Multi-Modal Insights for Complex EP Cases
Jeffrey Winterfield | Sotirios Nedros | Ravi Ranjan | Usha Tedrow
Innovations in imaging—ranging from real-time 3D/4D echo, advanced CT mapping to cardiac MRI—are reshaping electrophysiology. This session explores how novel visualization tools and AI-powered image processing can guide complex procedures while improving patient safety and outcomes.
01:15 PM (EDT)
– 02:00 PM (EDT)
Early Feasibility Studies and EP Innovation
Early Feasibility Studies and EP Innovation
Paul Wang | J. Peter Weiss
EP Collaboratory to share efforts between industry and early stage companies to promote EFS within the US to increase patient access to new technologies and to support device innovation.
01:15 PM (EDT)
– 02:00 PM (EDT)
Innovations in Antiarrhythmic Drug Therapy: Oxymoron or a Turning Point in the Field
Innovations in Antiarrhythmic Drug Therapy: Oxymoron or a Turning Point in the Field
Steven Lubitz
Catheter ablation has become the dominant form of therapeutic intervention for cardiac arrhythmias. However, preclinical development of new antiarrhythmic drugs is very robust. These new molecular entities are not limited to antagonism of membrane active ion channels, but target additional mechanisms of arrhythmogenesis. These drugs, their targets, and their potential ability to improve and disrupt current care paradigms will be reviewed in this session.
02:00 PM (EDT)
– 02:45 PM (EDT)
Clarity, Context, and Clinical Insight: The Future of Electrogram Intelligence – Powered by CathVision
Clarity, Context, and Clinical Insight: The Future of Electrogram Intelligence – Powered by CathVision
Dan Musat | Nicole Habel | Alexander Kushnir | Miguel Valderrabano
This session will explore signal fidelity and noise reduction in the EP lab, AI-augmented EGM interpretation, regulatory/validation/integration challenges for FDA approval and integration with 3D mapping systems, and clinical research opportunities using AI-driven procedural endpoints.
02:00 PM (EDT)
– 02:45 PM (EDT)
Development of Autonomous Mapping Systems
Development of Autonomous Mapping Systems
Sanjiv Narayan | Sabine Ernst | Shlomo Shpun | Jennifer N. Avari Silva
Self-driving cars, remote control of drones, and self-navigating planes are all current realities. However, mapping and ablation of cardiac arrhythmias is a completely human and labor-intensive endeavor, despite many advances over the years. This session will discuss the key barriers and potential solutions that may enable remote control of mapping and ablation as well as semi-autonomous systems for mapping and ablation.
02:45 PM (EDT)
– 03:30 PM (EDT)
Regulatory Science in a Changing Landscape for Device Trials
Regulatory Science in a Changing Landscape for Device Trials
This session will highlight the challenges, current best practices, and how innovation will impact regulatory science, with a focus on first-in-human device trials. The session will highlight shared and unique challenges in different regions of the world, including Asia, Europe, and North America. Attendees will be armed with a better understanding of the key barriers and facilitators for successful first-in-human trials.
03:00 PM (EDT)
– 03:45 AM (EDT)
AbstracX II
AbstracX II
Julie Shea (Moderator) | Advay Bhatt | Geoffroy Napon | Rachita Navara | Christopher Porterfield
This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.
03:00 PM (EDT)
– 03:45 PM (EDT)
Pulsed Field Ablation: The End of the Beginning
Pulsed Field Ablation: The End of the Beginning
Vivek Y. Reddy | Thomas Deneke
By the time of HRX 2025, pulsed field ablation will have been clinically available in the US for more than a year and a half. While first-gen systems have brought notable changes to EP, these first-generation systems only represent the very beginning of PFA. This session will focus on discussion of the key developments and advances for next generation PFA technologies, including advances in pulse sequences, catheter design, integration with electroanatomic mapping, and patient- and anatomic-specific custom lesion formation.
03:45 PM (EDT)
– 04:30 PM (EDT)
AbstracX III
AbstracX III
Matthew Kalscheur | Stuart Schecter | Jasjit Syan | Deepthy Varghese
This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.
03:45 PM (EDT)
– 04:30 PM (EDT)
AI for the Failing Heart: From Early Detection to Remote Monitoring and Predictive Analytics
AI for the Failing Heart: From Early Detection to Remote Monitoring and Predictive Analytics
Marat Fudim | Sarah Smith
As healthcare shifts toward proactive interventions, AI holds the promise of detecting heart failure before overt symptoms appear. In this session, experts will discuss how machine learning and big-data analytics can arm clinicians with real-time insights to intervene at the earliest sign of HF decompensation. Attendees will gain an understanding of predictive models, novel monitoring tools, and the challenges involved in implementing such technologies on a broad scale.
04:45 PM (EDT)
– 05:30 PM (EDT)
Cutting-Edge Ablation Techniques That Challenge Traditional Methods And Improve Patient Outcomes
Cutting-Edge Ablation Techniques That Challenge Traditional Methods And Improve Patient Outcomes
Jennifer N. Avari Silva
What’s next in the evolution of cardiac ablation technology? This session explores whether ease of use will translate into superior outcomes, the potential of novel energy sources, and the role of robotics, AR, and VR in procedural automation. Experts will also discuss the promise of computational modeling in personalizing ablation strategies—are we truly on the brink of precision ablation, or is clinical translation still a work in progress?
04:45 PM (EDT)
– 05:30 PM (EDT)
Innovative Educational Strategies for Patients and Professionals
Innovative Educational Strategies for Patients and Professionals
Jill Schaeffer | Jamie Harris | Jeroen Hendriks | Samuel F. Sears | Julie Shea | Mellanie True Hills
This session will explore cutting-edge approaches to patient education, focusing on the integration of digital tools and interactive platforms. Participants will gain insights into the latest best practices for educating patients and healthcare professionals, enhancing engagement, understanding, and overall patient outcomes.
05:30 PM (EDT)
– 06:30 PM (EDT)
AbstracX Happy Hour Session II – Powered by 91Life
AbstracX Happy Hour Session II – Powered by 91Life
Moez Alnazeer | Jina Choi | Mehak Dhande | Shruti Ganesan | James Ip | Suraya Hani Kamsani | Yaariv Khaykin | Abhishek Maan | Dan Musat | Alvaro Reyes-Quintero | William Swain | Meghan Reading Turchioe | Jason Yao
This engaging AbstracX Happy Hour session, powered by 91Life, kicks off with opening remarks from 91Life. Following the introduction, AbstracX presenters will present their work in a lively, informal setting designed to foster connection and conversation.
September 06, 2025
08:00 AM (EDT)
– 08:45 AM (EDT)
Novel Technologies are Here! Let’s Discuss Application
Novel Technologies are Here! Let’s Discuss Application
Sana Al-Khatib
Innovation in cardiology remains a central driving force to better patient care. This session explores how emerging technologies provide both opportunities and challenges to execute.
08:00 AM (EDT)
– 08:45 AM (EDT)
HRX Roundtable – HRS Research Network: Opportunities for Innovating How We Collaborate
HRX Roundtable – HRS Research Network: Opportunities for Innovating How We Collaborate
Mina K. Chung | Jagmeet Singh | J. Peter Weiss
This session will introduce a new initiative aimed at fostering collaboration among clinical, translational, and basic researchers. As a follow-up to presentations at Heart Rhythm 2025, the roundtable will highlight opportunities for innovation—particularly partnerships with industry—and explore how the Network will support mentorship, multi-center studies, and the development of a robust data warehouse. Discussions will cover data-sharing best practices, priority arrhythmia conditions, and the initiative’s potential to accelerate AI-driven research.
08:45 AM (EDT)
– 09:30 AM (EDT)
Wearables and the Future
Wearables and the Future
Jagmeet Singh | Derek Exner | Uma Srivatsa | Mintu Turakhia
The advent of multiple sensors in wearables begins to provide clinicians with a treasure trove of data of unknown impact and usefulness. This session will examine tech and the patient experience of employing it.
09:45 AM (EDT)
– 12:00 AM (EDT)
10:45 AM (EDT)
– 11:30 AM (EDT)
AI and Machine Learning in Electrophysiology: From Research to Implementation
AI and Machine Learning in Electrophysiology: From Research to Implementation
James O’Hara | Janet K. Han | Lisa Roelle | Heather Ross | Lauren Rousseau
We will discuss key issues surrounding interoperability and integration, exploring innovative solutions for seamless data flow across multiple monitoring systems. Additionally, we will evaluate the role of AI to support clinical decision-making, enhancing both patient outcomes and operational efficiency. Join us to explore the future of remote monitoring and data management, and how innovations in this field are shaping the future of healthcare
10:45 AM (EDT)
– 11:30 AM (EDT)
AbstracX IV
AbstracX IV
Oguz Akbilgic | Myrte Bartheis | Krishna Pundi
This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.
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Featured Session Block – Pulled from Title Field
2023 Speakers
Meet Our Speakers
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Michael Adjei-Mosi
Second Year Medical Student
Columbia University Vagelos College of Physicians and Surgeons
T. Massey Arrington
Assistant Vice President for Pulmonary, Respiratory, and Sleep Services
Wellstar Health System
Shanti Bansal
Chief Executive Officer | Electrophysiologist
Octagos Health | Houston Heart Rhythm PLLC
Maria Berkman
Head of MedTech, Broadview Ventures | Managing Director, Longview Ventures
Broadview Ventures and Longview Ventures
Julia Berzhanskaya
Program Director for trans-NIH REACH 2.0 and Innovator Support Lead
National Heart Lung and Blood Institute (NHLBI) Innovation& Commercialization Office
Neal Bhatia
Cardiac Electrophysiologist | Co-Director of the Complex Ventricular Tachycardia Ablation Program
Emory University Hospital System
Kenneth Bilchick
Associate Professor of Medicine | Clinical Cardiologist & Electrophysiologist
University of Virginia
Kristen Bova Campbell
Clinical Pharmacy Specialist and Senior Research Associate in Electrophysiology
Duke University Medical Center
Christopher Cheung
Cardiologist & Cardiac Electrophysiologist | Assistant Professor
Sunnybrook Health Sciences Centre | University of Toronto in Toronto, Canada
Mina K. Chung
Staff Cardiologist & Professor of Medicine in the Section of Pacing and Electrophysiology
Cleveland Clinic
Benjamin D’Souza
Associate Professor | Section Chief of Cardiac Electrophysiology and EP Lab Director
Penn Medicine
Kenneth Ellenbogen
Director of Clinical Cardiac Electrophysiology and Pacing | Kimmerling Chair of Cardiology | President
Virginia Commonwealth University | Heart Rhythm Society
Shavini Fernando
Founder & CEO | WBJ 40 under 40 (2022)| TedX Speaker | VR, WEB Designer Developer
OxiWear
Tony Fiola
Vice President & General Manager
Global Cardiac Diagnostic Services Franchise at Boston Scientific
Stephen Flaim
Senior Special Advisor & Investor-In-Residence | President | Director
National Heart Lung and Blood Institute, NIH | Flaim Partners Consulting | Haima Therapeutics
Ante Harxhi
Head of Therapeutic Area & Medical Innovation, Cardiovascular-Metabolics
Johnson & Johnson
Matthew Kalscheur
Cardiac Electrophysiologist & Clinical Informaticist
University of Wisconsin School of Medicine and Public Health
Dziugile Kersnauskaite
Resident Doctor Specializing in Cardiology
Vilnius University Hospital Santaros
Rohan Khera
Cardiologist-Data Scientist & Director of the Cardiovascular Data Science (CarDS) Lab | Clinical Director of the Center of Health Informatics and Analytics | Associate Editor
Yale University | CORE | JAMA
Douglas Kirsch
Medical Director | Clinical Professor in the Department of Neurology
Atrium Health Sleep Medicine | Wake Forest University School of Medicine
Robert Kowal
Vice President and General Manager, Cardiac Pacing Therapies | Cardiac Electrophysiologist
Medtronic
Jennifer Kozen
Assistant Director of the External Heart Rhythm and Rate Devices Team
US Food & Drug Administration
Erik Kulstad
Attending Physician | Professor of Emergency Medicine | Co-Founder
Parkland Hospital Emergency Department | University of Texas Southwestern Medical Center | Attune Medical
Dhanunjaya R. Lakkireddy
Executive Medical Director of the Kansas City Heart Rhythm Institute
HCA Midwest in Overland Park, Kansas
Adriana Mares
Student Researcher & Medical Student | Founder
Yale School of Medicine | Institute of Cardiology at El Paso
Michael Markl
Professor & Vice Chair for Research in the Department of Radiology | President
Northwestern University Feinberg School of Medicine | Society for Cardiovascular Magnetic Resonance
Rachita Navara
Co-founder & CEO of SafeBeat (YC S21) | EP Cardiologist | Engineer | NIH-funded Principal Investigator
SafeBeat Rx
Hitendra Patel
Medical Director Wellstar Sleep Program, Wellstar Pulmonary & Critical Care Medicine
WellStar Health System
Amber Seiler
Chief Operating Officer | EP Nurse Practitioner & Arrhythmia Program Services Coordinator
CV Remote Solutions | LeBauer Cardiology
Ravi Shah
Cardiac Electrophysiologist | Co-founder and Clinical Lead, AI in Cardiology Research Collaboration
Atrium Health Sanger HVI I Penn State
Karandeep Singh
Chief Health AI Officer | Jacobs Chancellor’s Endowed Chair
UC San Diego Health | UC San Diego
Jake Sunshine
Associate Professor | Research Scientist | Past Founder and Chief Medical Officer
UW School of Medicine | Google | Sound Life Sciences (acquired by Google)
Kirsten Tullia
Senior Vice President, Payment and Health Care Delivery Policy & Head of Research
Advanced Medical Technology Association (AdvaMed)
Manish Wadhwa
Chief Medical Officer | Cardiac Electrophysiologist
Philips Ambulatory Monitoring and Diagnostics | San Diego Arrhythmia Associates
Events
September 04, 2025
08:00 AM (EDT)
– 08:50 AM (EDT)
Innovation Summit Section l: Innovation in Cardiac Mapping
Innovation Summit Section l: Innovation in Cardiac Mapping
Jonathan Piccini | Shlomo Shpun | Sabine Ernst | Vadim Federov | Philip Haeusser | Mélèze Hocini | Jerome Kalifa | Devi Nair | Sanjiv Narayan
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
08:55 AM (EDT)
– 09:45 AM (EDT)
Innovation Summit Section ll: Innovation in Cardiac Ablation
Innovation Summit Section ll: Innovation in Cardiac Ablation
Devi Nair | Melanie Gunawardene | Sabine Ernst | H. Immo Lehmann | Vivek Y. Reddy | Andrea Sarkozy | Kalyanam Shivkumar
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
10:00 AM (EDT)
– 10:50 AM (EDT)
Innovation Summit Section III: Pacing & Implanted Device Therapy
Innovation Summit Section III: Pacing & Implanted Device Therapy
Emily Zeitler | Ulrika Birgersdotter-Green | Mikhael El-Chami | Avi Fischer | Devi Nair | Venkatakrishna Tholakanahalli | Niraj Varma
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
10:50 AM (EDT)
– 12:00 PM (EDT)
Innovation Summit Section IV: Diagnosis, Risk Stratification & Treatment of Arrhythmias
Innovation Summit Section IV: Diagnosis, Risk Stratification & Treatment of Arrhythmias
Elaine Wan | Patrick Boyle | Jennifer N. Avari Silva | Yaariv Khaykin | Zak Loring | Steven Lubitz | Devi Nair | Sotirios Nedios | Jagmeet Singh
Click on the session title to learn more and see a full agenda for this Innovation Summit section.
01:00 PM (EDT)
– 01:45 PM (EDT)
From Spark to Scale: Building a Culture of Innovation in MedTech
From Spark to Scale: Building a Culture of Innovation in MedTech
Kris Shah | Suneet Mittal
Kris Shah, former President of Baylis Medical and a driving force behind one of Canada’s most influential MedTech success stories, joins Dr. Suneet Mittal for a main tent conversation at HRX 2025. Together, they will explore how innovation can be intentionally cultivated—from early-stage ideation to global scale. Drawing from his leadership at Baylis Medical, Kris will share how he created an environment that empowered engineers and clinicians to challenge convention, embraced failure as a learning tool, and ultimately brought disruptive cardiovascular technologies to market. Attendees will gain insight into the strategic, cultural, and operational levers needed to sustain innovation in a highly regulated, risk-averse industry. Whether you’re a founder, physician, or executive, this session offers a blueprint for how to lead boldly and innovate with purpose.
02:00 PM (EDT)
– 02:45 PM (EDT)
AFib, AI, and the Future of Care: Revolution or Just Hype?
AFib, AI, and the Future of Care: Revolution or Just Hype?
Mintu Turakhia | Jeffrey Wessler
This session explores how AI-driven innovations are transforming atrial fibrillation (AF) management, from prevention to long-term care. Experts will discuss AI-powered digital education, solutions for early intervention, and technology’s role in addressing key risk factors like obesity, sleep apnea, and exercise. Is AI the game-changer in achieving sustainable AF care, or just another trend? Join us to find out.
02:00 PM (EDT)
– 02:45 PM (EDT)
Innovation Partner Roundtable – Continued Opportunities for Innovation in the Era of PFA – Powered by Kardium
Innovation Partner Roundtable – Continued Opportunities for Innovation in the Era of PFA – Powered by Kardium
As Pulsed Field Ablation (PFA) transitions from investigational to early commercial use, electrophysiology teams are reimagining workflows, tools, and treatment strategies. This expert roundtable will examine how early adopters are integrating PFA into clinical practice—from evolving lesion strategies and HD mapping techniques to contact sensing and directional energy delivery. Panelists will share first-hand insights on optimizing lesion durability, minimizing collateral damage, and tailoring ablation approaches for complex anatomies. With an eye toward next-generation technologies currently under evaluation, the discussion will also explore the innovations shaping the future of PFA and what’s needed to support continued progress in safety and efficacy.
02:00 PM (EDT)
– 02:45 PM (EDT)
Remote Monitoring and Data Management: Challenges and Innovations
Remote Monitoring and Data Management: Challenges and Innovations
Aileen Ferrick | Jessica Mullenix | Carissa Pistilli | Yekaterina Spivak | Julie Thomas | Amy Tucker | Rebecca Yapejian
In this session, we will delve into the evolving landscape of remote monitoring, addressing the increasing challenges associated with managing vast amounts of data collected from wearables, implantables, and external monitoring devices. We will explore the complexities of integrating data across diverse platforms, with a particular focus on overcoming interoperability barriers.
02:45 PM (EDT)
– 03:30 PM (EDT)
Pediatric EP and Cardiac Tech: Lifesaver or Just the Start?
Pediatric EP and Cardiac Tech: Lifesaver or Just the Start?
Brynn Dechert-Crooks | Benjamin Hale | Jamie Harris | Lisa Roelle | Nicholas Von Bergen
From life-changing interventions to emotional uncertainties, how does cardiac technology shape the journey of children and young adults with arrhythmias? This session explores the evolving role of electrophysiology (EP) in pediatrics, the impact of cutting-edge devices, and the patient experience—balancing fear, hope, and the promise of innovation. Are we maximizing technology’s potential, or is is there more to uncover in improving outcomes and quality of life for young patients?
02:45 PM (EDT)
– 03:30 PM (EDT)
HRX Roundtable – Non-Watch Wearables in Cardiovascular Care
HRX Roundtable – Non-Watch Wearables in Cardiovascular Care
Marco Perez | Arik Ben Ishay | Derek Exner | Yaariv Kahykin
From smart rings and adhesive patches to smart clothing and implantables, non-watch wearables are reshaping how we monitor, diagnose, and manage cardiovascular disease outside traditional clinical settings. This roundtable will explore the expanding landscape of non-watch wearable technologies, their clinical utility in arrhythmia detection, heart failure monitoring, and vital sign assessment, and the challenges of data validation, workflow integration, and reimbursement. Panelists will share insights on current use cases, patient engagement strategies, and the future promise of these emerging tools in delivering continuous, personalized cardiovascular care.
02:45 PM (EDT)
– 03:30 PM (EDT)
Sudden Cardiac Arrest Session
Sudden Cardiac Arrest Session
Mina K. Chung | Alan Cheng | Sumeet Chugh | Richard Price | Monique Starks | Jake Sunshine
SCA is a persistent public health problem, but little has changed over the past several decades. This session will highlight new approaches to the prevention and treatment of SCA that leverage innovative technologies and systems of care. Special attention will be given to how different technologies, education, and predictive analytics can synergize to improve the problem of SCA and improve outcomes.
03:45 PM (EDT)
– 04:30 PM (EDT)
Personalized Care Through Digital Twins – Foundational or Fantasy?
Personalized Care Through Digital Twins – Foundational or Fantasy?
Natalia Trayanova | Patrick Boyle | Jonathan Chrispin | Tanmay Gokhale | Liat Tsoref
Digital twins offer the promise to develop, test, and validate potential personalized solutions for heart rhythm care that are unique to a given individual and their myocardial substrate. Early studies have been promising. However, there are significant challenges from several different areas including operational, computational, and efficacy. This session will engage in discussing whether digital twins will become a foundational core of EP care or remain a fantasy.
03:45 PM (EDT)
– 04:30 PM (EDT)
Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
Dominic Abrams | Vassilios Bezzerides | Gabriel Brooks | Samuel Hall | Cain McClary
Inherited arrhythmia syndromes and cardiomyopathies pose a significant clinic challenge, with suboptimal treatment and a large unmet need. Over the last decade several new therapies have been developed which target the underlying genetic and molecular causes of these conditions, and many are progressing from pre-clinical research to clinical trials. These discoveries offer a potential paradigm shift in treatment strategies and quality of life for patients. This panel focused on novel genetic and molecular therapies for inherited arrhythmia syndromes and arrhythmogenic cardiomyopathies will bring together experts with a broad range of experience including venture capital, clinicians, translational scientists, and biotech. The session will address a wide range of topics from lab discovery to commercialization.
03:45 PM (EDT)
– 04:30 PM (EDT)
HRX Roundtable – Using Large Language Models in Clinical Practice
HRX Roundtable – Using Large Language Models in Clinical Practice
Hamid Ghanbari | Jacqueline Shreibati
Large Language Models (LLMs) are rapidly moving from experimental tools to real-world clinical assistants. This roundtable explores how LLMs are being integrated into everyday workflows across cardiology and beyond—powering clinical documentation, decision support, patient communication, and medical education. Panelists will discuss emerging use cases, real-world implementation challenges, and ethical considerations such as bias, data privacy, and regulatory oversight. Join us for a pragmatic, frontline view of how AI is reshaping the clinician-patient interface and what it will take to move from promise to practice.
03:45 PM (EDT)
– 04:30 PM (EDT)
Top 5 AbstracX
Top 5 AbstracX
Daniel Morin (Moderator) | Yaariv Khaykin | Bobak Mosadegh | Nobunari Tomura | Bryant Wyatt
The Top 5 scoring AbstracX Researchers will share their research.
03:45 PM (EDT)
– 04:30 PM (EDT)
Innovation Partner Roundtable: Potential of AI to Improve CIED Remote Monitoring – Powered by 91Life
Innovation Partner Roundtable: Potential of AI to Improve CIED Remote Monitoring – Powered by 91Life
Prashanthan Sanders | Meghan Reading Turchioe | Niraj Varma
This session will explore the opportunity for AI to assist with assessment of device interrogations, arrhythmia detection and identification, alert management and generation of clinical synopsis to enhance efficiency of CIED remote monitoring. The session will also explore how AI can enhance “population level” understanding of a large CIED remote monitoring program.
04:30 PM (EDT)
– 05:15 PM (EDT)
Evolution, Integration, and Disruption of Ultrasound Technologies in the EP Laboratory
Evolution, Integration, and Disruption of Ultrasound Technologies in the EP Laboratory
Amin Al-Ahmad | Luigi Di Biase | Christoph Hennersperger
There is an unprecedented surge in innovation surrounding intracardiac ultrasound and its integration into electrophysiologic care. Future iterations of 4-D intracardiac ultrasound, next-generation integration into mapping systems, and the use of ultrasound for therapeutic purposes all have the potential to significantly change practice. This session will review these key innovations and how they may improve care in the EP laboratory.
04:30 PM (EDT)
– 05:15 PM (EDT)
HRX Roundtable – Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
HRX Roundtable – Novel Molecular and Genetic Therapies for Inherited Arrhythmia Syndrome and Arrhythmogenic Cardiomyopathies
Gabriel Brooks | Vassillios Bezzerides | David Milan | Samuel F. Sears
Current treatments for inherited arrhythmias focus on medical therapy and cardiac implanted electronic devices. While they suppress arrhythmias and prevent fatal sequelae they do not address the fundamental underlying cause of the disease. While gene therapy has been a theoretical solution to fix the underlying cause of inherited arrhythmias, recent innovations are finally bringing these therapies closer to clinical care. This session will explore the different genetic therapies in development for a variety of disorders and how they will impact persons with inherited arrhythmias from a clinical and psychological standpoint.
04:30 PM (EDT)
– 05:15 PM (EDT)
HRX Roundtable – Innovation in PPG Technology
HRX Roundtable – Innovation in PPG Technology
Dominik K Linz | Lars Grieten | Nassir Marrouche | Yosef Safi Harb | Emma Svennberg
PPG has rapidly evolved from a consumer wellness tool into a promising clinical modality with wide-ranging applications in cardiovascular care. This roundtable will explore cutting-edge innovations in PPG technology and how it is being deployed to transform detection, diagnosis, and disease management. From arrhythmia monitoring to blood pressure estimation, sleep apnea screening, and heart failure assessment, PPG-based tools are reshaping how and where care is delivered—especially when integrated into wearables, smartphones, and remote monitoring platforms. Experts from digital health startups, academic research, and clinical practice will examine key advances in signal processing, AI-enhanced analytics, and device miniaturization. We’ll also tackle the regulatory, validation, and clinical integration challenges that must be addressed to move from promise to practice.
04:30 PM (EDT)
– 05:15 PM (EDT)
Clinical Workflow: Interoperability, Decision-Making, and Solutions – What’s the Missing Link?
Clinical Workflow: Interoperability, Decision-Making, and Solutions – What’s the Missing Link?
David Slotwiner
This session explores how AI integration, EMR advancements, and remote monitoring can enhance physician decision-making, streamline workflows, and improve patient care. Panelists will discuss the impact of AI on billing and physician hours, the role of device-driven insights in heart failure management, and how RNs and APPs contribute to effective communication and data management. Join us for an insightful discussion on leveraging technology to optimize clinical efficiency and patient outcomes.
04:30 PM (EDT)
– 05:15 PM (EDT)
AI at the Point of Care: Redesigning Documentation for Clinicians
AI at the Point of Care: Redesigning Documentation for Clinicians
Dhanunjaya R. Lakkireddy
From dictation software to full-blown natural language processing assistants, AI-based documentation tools promise to free clinicians from the tedium of charting. Physician burnout is on the rise—can AI-driven documentation help turn the tide? Strategies for successful change management, physician buy-in, and ongoing system optimization will be highlighted. How do we ensure data accuracy, privacy, and seamless integration into diverse electronic health records? Panelists will discuss the practical implementation of AI-assisted documentation and patient communication, while maintaining patient-centered care.
05:30 PM (EDT)
– 06:30 PM (EDT)
AbstracX Happy Hour Session I – Powered by 91Life
AbstracX Happy Hour Session I – Powered by 91Life
Siddharth Agarwal | Leart Ajvazaj | Myrte Bartheis | Wen-Han Cheng | Mithilesh Das | Marye Gleva | Masahiro Makino | Nicolle Milstein | Geoffroy Napon | Ajay Tripuraneni
This engaging AbstracX Happy Hour session, powered by 91Life, kicks off with opening remarks from 91Life. Following the introduction, AbstracX presenters will present their work in a lively, informal setting designed to foster connection and conversation.
September 05, 2025
08:45 AM (EDT)
– 09:30 AM (EDT)
Main Tent Session Featuring Doron Harlev
Main Tent Session Featuring Doron Harlev
Doron Harlev | Jonathan Piccini
09:45 AM (EDT)
– 10:30 AM (EDT)
HRX AP Shark Tank: Fueling Innovation, Advancing Patient Care
HRX AP Shark Tank: Fueling Innovation, Advancing Patient Care
The HRX AP Shark Tank is an electrifying competition where allied professionals present groundbreaking ideas that have the potential to revolutionize patient care and advance electrophysiology practice. This event provides a unique platform for APs to pitch their most innovative research concepts, workflow enhancements, or practice-changing solutions to a panel of expert “sharks.”
How It Works:
– Top 5 Finalists: Authors of the five top‐rated submissions will be invited to present their ideas in person at HRX 2025.
– Expert Mentorship: Finalists will receive mentorship prior to their presentation to refine their ideas and maximize their impact.
– Live Pitch Session: Finalists will pitch their ideas live at HRX 2025 to a panel “sharks” comprised of industry leaders and EP experts.
– Winner Recognition: The most compelling idea will be awarded top honors, gaining visibility and credibility within the AP and EP communities.
09:45 AM (EDT)
– 10:30 AM (EDT)
Innovations in Autonomic Therapies for Atrial Fibrillation
Innovations in Autonomic Therapies for Atrial Fibrillation
Jonathan Piccini | Shih-Ann Chen | Marat Fudim | Stavros Stavrakis | Kalyanam Shivkumar
The autonomic nervous system is known to play a critical role in the initiation and/or triggering of many arrhythmias, including atrial fibrillation. Autonomic therapies have moved well-beyond isolated ablation of cardiac ganglionated plexi. This session will review the innovations that have expanded autonomic therapies, including tragus stimulation, renal sympathetic denervation, and future innovations for additional interventions.
09:45 AM (EDT)
– 10:30 AM (EDT)
Are Digital Innovations Accelerating Advances in Gene Therapy?
Are Digital Innovations Accelerating Advances in Gene Therapy?
With gene therapy advancing rapidly, how do digital innovations accelerate its impact on cardiovascular disease? This session explores the evolution of gene therapy trials, cutting-edge breakthroughs, and the role of AI, big data, and digital platforms in research, patient monitoring, and treatment optimization. Hear from experts and patient advocates as we examine whether technology is the key to making gene therapy more accessible, efficient, and transformative. Are we on the verge of a revolution, or just scratching the surface?
10:30 AM (EDT)
– 11:15 AM (EDT)
The Permanent Pacing of Tomorrow
The Permanent Pacing of Tomorrow
Mikhael El-Chami | Neal Bhatia | Janet K. Han | Anne Kroman | Kathryn Hilpisch
This session will detail the possibilities, potential technologies, and likely pathways for permanent pacing in the future. Specifically, this session will explore next generation pacing technologies, including but not limited to advances in leadless pacing, micro-devices, new epicardial pacing interventions, pacing for HFpE, and physiologic atrial pacing.
10:30 AM (EDT)
– 11:15 AM (EDT)
Innovation Partner Roundtable – Rethinking Rhythm Care: Technology-Driven Trends in ECG Monitoring Reshaping EP Practice – Powered by iRhythm
Innovation Partner Roundtable – Rethinking Rhythm Care: Technology-Driven Trends in ECG Monitoring Reshaping EP Practice – Powered by iRhythm
Suneet Mittal | Joshua Lampert
This roundtable will examine how long-term continuous ECG monitoring, remote diagnostics, and AI-assisted interpretation are enabling more accurate arrhythmia detection and more confident clinical decisions. We’ll discuss key applications including the ability to scan large streams of recorded data, AF and PVC burden assessment, ablation follow-up, and early identification of overlooked arrhythmias through the lens of what’s next for EPs in a digital-first world. We’ll discuss different AI approaches (high sensitivity, high specificity, multiple layers) and the technicians-in-the-loop versus fully autonomous AI. We’ll what’s next for ambulatory ECG AI, including LV dysfunction, sleep apnea, structural heart disease, and even hospitalization and health care utilization.
12:30 PM (EDT)
– 01:15 PM (EDT)
Heart Rhythm Innovation Morbidity and Mortality Conference – Avoiding Fatal Pitfalls
Heart Rhythm Innovation Morbidity and Mortality Conference – Avoiding Fatal Pitfalls
Avi Fischer | Daniel Cantillon | Jennifer N. Avari Silva
Not all innovation is successful. Many potential innovations fail in the pre-clinical or early testing phases – often for common reasons. This session will discuss the potential pitfalls in device development and how innovators can navigate these challenges with greater confidence by avoiding mistakes and missteps. The panel will discuss their “dream” innovations that didn’t come to fruition – and what they learned.
12:30 PM (EDT)
– 01:15 PM (EDT)
HRX Roundtable – Registries & Data Collection of the Future – New Ways to Learn
HRX Roundtable – Registries & Data Collection of the Future – New Ways to Learn
Sana Al-Khatib | Luigi Di Biase | Paul Varosy | Emily Zeitler
As digital innovation reshapes the electrophysiology landscape, the way we collect and learn from clinical data must evolve in parallel. This forward-looking roundtable will explore next-generation registries and data platforms designed to reduce abstraction burden, enhance clinical insights, and accelerate quality improvement across diverse practice settings. With the Heart Rhythm Society’s newly announced PFA Data Entry Platform—a clinician-led, AI-enhanced alternative to traditional registries—as a central case study, panelists will discuss how emerging models can modernize data collection for novel technologies like Pulsed Field Ablation. We’ll examine core design elements such as longitudinal tracking, integrated data sources, standardized APIs, and real-time benchmarking tools that support both clinical care and research.
12:30 PM (EDT)
– 01:15 PM (EDT)
Imaging 2.0: Multi-Modal Insights for Complex EP Cases
Imaging 2.0: Multi-Modal Insights for Complex EP Cases
Jeffrey Winterfield | Sotirios Nedros | Ravi Ranjan | Usha Tedrow
Innovations in imaging—ranging from real-time 3D/4D echo, advanced CT mapping to cardiac MRI—are reshaping electrophysiology. This session explores how novel visualization tools and AI-powered image processing can guide complex procedures while improving patient safety and outcomes.
01:15 PM (EDT)
– 02:00 PM (EDT)
Early Feasibility Studies and EP Innovation
Early Feasibility Studies and EP Innovation
Paul Wang | J. Peter Weiss
EP Collaboratory to share efforts between industry and early stage companies to promote EFS within the US to increase patient access to new technologies and to support device innovation.
01:15 PM (EDT)
– 02:00 PM (EDT)
Innovations in Antiarrhythmic Drug Therapy: Oxymoron or a Turning Point in the Field
Innovations in Antiarrhythmic Drug Therapy: Oxymoron or a Turning Point in the Field
Steven Lubitz
Catheter ablation has become the dominant form of therapeutic intervention for cardiac arrhythmias. However, preclinical development of new antiarrhythmic drugs is very robust. These new molecular entities are not limited to antagonism of membrane active ion channels, but target additional mechanisms of arrhythmogenesis. These drugs, their targets, and their potential ability to improve and disrupt current care paradigms will be reviewed in this session.
02:00 PM (EDT)
– 02:45 PM (EDT)
Clarity, Context, and Clinical Insight: The Future of Electrogram Intelligence – Powered by CathVision
Clarity, Context, and Clinical Insight: The Future of Electrogram Intelligence – Powered by CathVision
Dan Musat | Nicole Habel | Alexander Kushnir | Miguel Valderrabano
This session will explore signal fidelity and noise reduction in the EP lab, AI-augmented EGM interpretation, regulatory/validation/integration challenges for FDA approval and integration with 3D mapping systems, and clinical research opportunities using AI-driven procedural endpoints.
02:00 PM (EDT)
– 02:45 PM (EDT)
Development of Autonomous Mapping Systems
Development of Autonomous Mapping Systems
Sanjiv Narayan | Sabine Ernst | Shlomo Shpun | Jennifer N. Avari Silva
Self-driving cars, remote control of drones, and self-navigating planes are all current realities. However, mapping and ablation of cardiac arrhythmias is a completely human and labor-intensive endeavor, despite many advances over the years. This session will discuss the key barriers and potential solutions that may enable remote control of mapping and ablation as well as semi-autonomous systems for mapping and ablation.
02:45 PM (EDT)
– 03:30 PM (EDT)
Regulatory Science in a Changing Landscape for Device Trials
Regulatory Science in a Changing Landscape for Device Trials
This session will highlight the challenges, current best practices, and how innovation will impact regulatory science, with a focus on first-in-human device trials. The session will highlight shared and unique challenges in different regions of the world, including Asia, Europe, and North America. Attendees will be armed with a better understanding of the key barriers and facilitators for successful first-in-human trials.
03:00 PM (EDT)
– 03:45 AM (EDT)
AbstracX II
AbstracX II
Julie Shea (Moderator) | Advay Bhatt | Geoffroy Napon | Rachita Navara | Christopher Porterfield
This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.
03:00 PM (EDT)
– 03:45 PM (EDT)
Pulsed Field Ablation: The End of the Beginning
Pulsed Field Ablation: The End of the Beginning
Vivek Y. Reddy | Thomas Deneke
By the time of HRX 2025, pulsed field ablation will have been clinically available in the US for more than a year and a half. While first-gen systems have brought notable changes to EP, these first-generation systems only represent the very beginning of PFA. This session will focus on discussion of the key developments and advances for next generation PFA technologies, including advances in pulse sequences, catheter design, integration with electroanatomic mapping, and patient- and anatomic-specific custom lesion formation.
03:45 PM (EDT)
– 04:30 PM (EDT)
AbstracX III
AbstracX III
Matthew Kalscheur | Stuart Schecter | Jasjit Syan | Deepthy Varghese
This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.
03:45 PM (EDT)
– 04:30 PM (EDT)
AI for the Failing Heart: From Early Detection to Remote Monitoring and Predictive Analytics
AI for the Failing Heart: From Early Detection to Remote Monitoring and Predictive Analytics
Marat Fudim | Sarah Smith
As healthcare shifts toward proactive interventions, AI holds the promise of detecting heart failure before overt symptoms appear. In this session, experts will discuss how machine learning and big-data analytics can arm clinicians with real-time insights to intervene at the earliest sign of HF decompensation. Attendees will gain an understanding of predictive models, novel monitoring tools, and the challenges involved in implementing such technologies on a broad scale.
04:45 PM (EDT)
– 05:30 PM (EDT)
Cutting-Edge Ablation Techniques That Challenge Traditional Methods And Improve Patient Outcomes
Cutting-Edge Ablation Techniques That Challenge Traditional Methods And Improve Patient Outcomes
Jennifer N. Avari Silva
What’s next in the evolution of cardiac ablation technology? This session explores whether ease of use will translate into superior outcomes, the potential of novel energy sources, and the role of robotics, AR, and VR in procedural automation. Experts will also discuss the promise of computational modeling in personalizing ablation strategies—are we truly on the brink of precision ablation, or is clinical translation still a work in progress?
04:45 PM (EDT)
– 05:30 PM (EDT)
Innovative Educational Strategies for Patients and Professionals
Innovative Educational Strategies for Patients and Professionals
Jill Schaeffer | Jamie Harris | Jeroen Hendriks | Samuel F. Sears | Julie Shea | Mellanie True Hills
This session will explore cutting-edge approaches to patient education, focusing on the integration of digital tools and interactive platforms. Participants will gain insights into the latest best practices for educating patients and healthcare professionals, enhancing engagement, understanding, and overall patient outcomes.
05:30 PM (EDT)
– 06:30 PM (EDT)
AbstracX Happy Hour Session II – Powered by 91Life
AbstracX Happy Hour Session II – Powered by 91Life
Moez Alnazeer | Jina Choi | Mehak Dhande | Shruti Ganesan | James Ip | Suraya Hani Kamsani | Yaariv Khaykin | Abhishek Maan | Dan Musat | Alvaro Reyes-Quintero | William Swain | Meghan Reading Turchioe | Jason Yao
This engaging AbstracX Happy Hour session, powered by 91Life, kicks off with opening remarks from 91Life. Following the introduction, AbstracX presenters will present their work in a lively, informal setting designed to foster connection and conversation.
September 06, 2025
08:00 AM (EDT)
– 08:45 AM (EDT)
Novel Technologies are Here! Let’s Discuss Application
Novel Technologies are Here! Let’s Discuss Application
Sana Al-Khatib
Innovation in cardiology remains a central driving force to better patient care. This session explores how emerging technologies provide both opportunities and challenges to execute.
08:00 AM (EDT)
– 08:45 AM (EDT)
HRX Roundtable – HRS Research Network: Opportunities for Innovating How We Collaborate
HRX Roundtable – HRS Research Network: Opportunities for Innovating How We Collaborate
Mina K. Chung | Jagmeet Singh | J. Peter Weiss
This session will introduce a new initiative aimed at fostering collaboration among clinical, translational, and basic researchers. As a follow-up to presentations at Heart Rhythm 2025, the roundtable will highlight opportunities for innovation—particularly partnerships with industry—and explore how the Network will support mentorship, multi-center studies, and the development of a robust data warehouse. Discussions will cover data-sharing best practices, priority arrhythmia conditions, and the initiative’s potential to accelerate AI-driven research.
08:45 AM (EDT)
– 09:30 AM (EDT)
Wearables and the Future
Wearables and the Future
Jagmeet Singh | Derek Exner | Uma Srivatsa | Mintu Turakhia
The advent of multiple sensors in wearables begins to provide clinicians with a treasure trove of data of unknown impact and usefulness. This session will examine tech and the patient experience of employing it.
09:45 AM (EDT)
– 12:00 AM (EDT)
10:45 AM (EDT)
– 11:30 AM (EDT)
AI and Machine Learning in Electrophysiology: From Research to Implementation
AI and Machine Learning in Electrophysiology: From Research to Implementation
James O’Hara | Janet K. Han | Lisa Roelle | Heather Ross | Lauren Rousseau
We will discuss key issues surrounding interoperability and integration, exploring innovative solutions for seamless data flow across multiple monitoring systems. Additionally, we will evaluate the role of AI to support clinical decision-making, enhancing both patient outcomes and operational efficiency. Join us to explore the future of remote monitoring and data management, and how innovations in this field are shaping the future of healthcare
10:45 AM (EDT)
– 11:30 AM (EDT)
AbstracX IV
AbstracX IV
Oguz Akbilgic | Myrte Bartheis | Krishna Pundi
This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.
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