Kris Shah, former President of Baylis Medical and a driving force behind one of Canada’s most influential MedTech success stories, joins Dr. Suneet Mittal for a main tent conversation at HRX 2025. Together, they will explore how innovation can be intentionally cultivated—from early-stage ideation to global scale. Drawing from his leadership at Baylis Medical, Kris will share how he created an environment that empowered engineers and clinicians to challenge convention, embraced failure as a learning tool, and ultimately brought disruptive cardiovascular technologies to market. Attendees will gain insight into the strategic, cultural, and operational levers needed to sustain innovation in a highly regulated, risk-averse industry. Whether you’re a founder, physician, or executive, this session offers a blueprint for how to lead boldly and innovate with purpose.

This session explores how AI-driven innovations are transforming atrial fibrillation (AF) management, from prevention to long-term care. Experts will discuss AI-powered digital education, solutions for early intervention, and technology’s role in addressing key risk factors like obesity, sleep apnea, and exercise. Is AI the game-changer in achieving sustainable AF care, or just another trend? Join us to find out.

As Pulsed Field Ablation (PFA) transitions from investigational to early commercial use, electrophysiology teams are reimagining workflows, tools, and treatment strategies. This expert roundtable will examine how early adopters are integrating PFA into clinical practice—from evolving lesion strategies and HD mapping techniques to contact sensing and directional energy delivery. Panelists will share first-hand insights on optimizing lesion durability, minimizing collateral damage, and tailoring ablation approaches for complex anatomies. With an eye toward next-generation technologies currently under evaluation, the discussion will also explore the innovations shaping the future of PFA and what’s needed to support continued progress in safety and efficacy.

In this session, we will delve into the evolving landscape of remote monitoring, addressing the increasing challenges associated with managing vast amounts of data collected from wearables, implantables, and external monitoring devices. We will explore the complexities of integrating data across diverse platforms, with a particular focus on overcoming interoperability barriers.

As AI begins to transform the EP landscape, high-quality data collection in the EP laboratory has become a foundational requirement. However, the process of collecting, structuring, labeling, and integrating multimodal EP data—including signals, imaging, annotations, and procedural metadata—presents significant technical, regulatory, and operational challenges. This roundtable will convene EP clinicians, data scientists, digital health leaders, and industry innovators to explore how data generated during routine EP procedures can be leveraged to power AI algorithms. Topics will include interoperability between EP lab systems, data ownership and governance, strategies for annotation and ground truth creation, privacy-preserving data sharing, and collaborative AI development between health systems and industry. Panelists will also showcase early successes and lessons learned from existing AI initiatives in arrhythmia detection, ablation guidance, and post-procedure outcomes prediction.

From smart rings and adhesive patches to smart clothing and implantables, non-watch wearables are reshaping how we monitor, diagnose, and manage cardiovascular disease outside traditional clinical settings. This roundtable will explore the expanding landscape of non-watch wearable technologies, their clinical utility in arrhythmia detection, heart failure monitoring, and vital sign assessment, and the challenges of data validation, workflow integration, and reimbursement. Panelists will share insights on current use cases, patient engagement strategies, and the future promise of these emerging tools in delivering continuous, personalized cardiovascular care.

SCA is a persistent public health problem, but little has changed over the past several decades. This session will highlight new approaches to the prevention and treatment of SCA that leverage innovative technologies and systems of care. Special attention will be given to how different technologies, education, and predictive analytics can synergize to improve the problem of SCA and improve outcomes.

From life-changing interventions to emotional uncertainties, how does cardiac technology shape the journey of children and young adults with arrhythmias? This session explores the evolving role of electrophysiology (EP) in pediatrics, the impact of cutting-edge devices, and the patient experience—balancing fear, hope, and the promise of innovation. Are we maximizing technology’s potential, or is is there more to uncover in improving outcomes and quality of life for young patients?

This session will explore the opportunity for AI to assist with assessment of device interrogations, arrhythmia detection and identification, alert management and generation of clinical synopsis to enhance efficiency of CIED remote monitoring. The session will also explore how AI can enhance “population level” understanding of a large CIED remote monitoring program.

Inherited arrhythmia syndromes and cardiomyopathies pose a significant clinic challenge, with suboptimal treatment and a large unmet need. Over the last decade several new therapies have been developed which target the underlying genetic and molecular causes of these conditions, and many are progressing from pre-clinical research to clinical trials. These discoveries offer a potential paradigm shift in treatment strategies and quality of life for patients. This panel focused on novel genetic and molecular therapies for inherited arrhythmia syndromes and arrhythmogenic cardiomyopathies will bring together experts with a broad range of experience including venture capital, clinicians, translational scientists, and biotech. The session will address a wide range of topics from lab discovery to commercialization.

Large Language Models (LLMs) are rapidly moving from experimental tools to real-world clinical assistants. This roundtable explores how LLMs are being integrated into everyday workflows across cardiology and beyond—powering clinical documentation, decision support, patient communication, and medical education. Panelists will discuss emerging use cases, real-world implementation challenges, and ethical considerations such as bias, data privacy, and regulatory oversight. Join us for a pragmatic, frontline view of how AI is reshaping the clinician-patient interface and what it will take to move from promise to practice.

Digital twins offer the promise to develop, test, and validate potential personalized solutions for heart rhythm care that are unique to a given individual and their myocardial substrate. Early studies have been promising. However, there are significant challenges from several different areas including operational, computational, and efficacy. This session will engage in discussing whether digital twins will become a foundational core of EP care or remain a fantasy.

The Top 5 scoring AbstracX Researchers will share their research.

Current treatments for inherited arrhythmias focus on medical therapy and cardiac implanted electronic devices. While they suppress arrhythmias and prevent fatal sequelae they do not address the fundamental underlying cause of the disease. While gene therapy has been a theoretical solution to fix the underlying cause of inherited arrhythmias, recent innovations are finally bringing these therapies closer to clinical care. This session will explore the different genetic therapies in development for a variety of disorders and how they will impact persons with inherited arrhythmias from a clinical and psychological standpoint.

This session explores how AI integration, EMR advancements, and remote monitoring can enhance physician decision-making, streamline workflows, and improve patient care. Panelists will discuss the impact of AI on billing and physician hours, the role of device-driven insights in heart failure management, and how RNs and APPs contribute to effective communication and data management. Join us for an insightful discussion on leveraging technology to optimize clinical efficiency and patient outcomes.

There is an unprecedented surge in innovation surrounding intracardiac ultrasound and its integration into electrophysiologic care. Future iterations of 4-D intracardiac ultrasound, next-generation integration into mapping systems, and the use of ultrasound for therapeutic purposes all have the potential to significantly change practice. This session will review these key innovations and how they may improve care in the EP laboratory.

From dictation software to full-blown natural language processing assistants, AI-based documentation tools promise to free clinicians from the tedium of charting. Physician burnout is on the rise—can AI-driven documentation help turn the tide? Strategies for successful change management, physician buy-in, and ongoing system optimization will be highlighted. How do we ensure data accuracy, privacy, and seamless integration into diverse electronic health records? Panelists will discuss the practical implementation of AI-assisted documentation and patient communication, while maintaining patient-centered care.

PPG has rapidly evolved from a consumer wellness tool into a promising clinical modality with wide-ranging applications in cardiovascular care. This roundtable will explore cutting-edge innovations in PPG technology and how it is being deployed to transform detection, diagnosis, and disease management. From arrhythmia monitoring to blood pressure estimation, sleep apnea screening, and heart failure assessment, PPG-based tools are reshaping how and where care is delivered—especially when integrated into wearables, smartphones, and remote monitoring platforms. Experts from digital health startups, academic research, and clinical practice will examine key advances in signal processing, AI-enhanced analytics, and device miniaturization. We’ll also tackle the regulatory, validation, and clinical integration challenges that must be addressed to move from promise to practice.

Join our expert panel as they explore the latest research on AI-powered AF risk assessment, revealing what AI algorithms tend to focus on when identifying high-risk patients. They will discuss the potential of AI has in improving predictive accuracy and how this may affect patient treatment plans going forward. AI-assisted forecasting is only going to improve, so don’t miss this opportunity to discuss AF risk assessment and how AI is transforming patient care.

The autonomic nervous system is known to play a critical role in the initiation and/or triggering of many arrhythmias, including atrial fibrillation. Autonomic therapies have moved well-beyond isolated ablation of cardiac ganglionated plexi. This session will review the innovations that have expanded autonomic therapies, including tragus stimulation, renal sympathetic denervation, and future innovations for additional interventions.

This roundtable will examine how long-term continuous ECG monitoring, remote diagnostics, and AI-assisted interpretation are enabling more accurate arrhythmia detection and more confident clinical decisions. We’ll discuss key applications including the ability to scan large streams of recorded data, AF and PVC burden assessment, ablation follow-up, and early identification of overlooked arrhythmias through the lens of what’s next for EPs in a digital-first world. We’ll discuss different AI approaches (high sensitivity, high specificity, multiple layers) and the technicians-in-the-loop versus fully autonomous AI. We’ll what’s next for ambulatory ECG AI, including LV dysfunction, sleep apnea, structural heart disease, and even hospitalization and health care utilization.

This session will detail the possibilities, potential technologies, and likely pathways for permanent pacing in the future. Specifically, this session will explore next generation pacing technologies, including but not limited to advances in leadless pacing, micro-devices, new epicardial pacing interventions, pacing for HFpE, and physiologic atrial pacing.

As the volume and complexity of digital health data continues to grow—from CIEDs and wearables to remote vitals and EMRs—advanced practice providers (APPs) are often on the front lines, tasked with translating disparate data streams into meaningful clinical action. This roundtable, led by APPs, will tackle the challenges of data fragmentation and explore strategies to streamline workflow, reduce burnout, and improve patient outcomes through platform consolidation. Panelists will share real-world insights, examine interoperability gaps, and discuss emerging tools and vendor partnerships that hold promise for a more unified data ecosystem.

As digital innovation reshapes the electrophysiology landscape, the way we collect and learn from clinical data must evolve in parallel. This forward-looking roundtable will explore next-generation registries and data platforms designed to reduce abstraction burden, enhance clinical insights, and accelerate quality improvement across diverse practice settings. With the Heart Rhythm Society’s newly announced PFA Data Entry Platform—a clinician-led, AI-enhanced alternative to traditional registries—as a central case study, panelists will discuss how emerging models can modernize data collection for novel technologies like Pulsed Field Ablation. We’ll examine core design elements such as longitudinal tracking, integrated data sources, standardized APIs, and real-time benchmarking tools that support both clinical care and research.

Not all innovation is successful. Many potential innovations fail in the pre-clinical or early testing phases – often for common reasons. This session will discuss the potential pitfalls in device development and how innovators can navigate these challenges with greater confidence by avoiding mistakes and missteps. The panel will discuss their “dream” innovations that didn’t come to fruition – and what they learned.

Innovations in imaging—ranging from real-time 3D/4D echo, advanced CT mapping to cardiac MRI—are reshaping electrophysiology. This session explores how novel visualization tools and AI-powered image processing can guide complex procedures while improving patient safety and outcomes. 

EP Collaboratory to share efforts between industry and early stage companies to promote EFS within the US to increase patient access to new technologies and to support device innovation.

Catheter ablation has become the dominant form of therapeutic intervention for cardiac arrhythmias. However, preclinical development of new antiarrhythmic drugs is very robust. These new molecular entities are not limited to antagonism of membrane active ion channels, but target additional mechanisms of arrhythmogenesis. These drugs, their targets, and their potential ability to improve and disrupt current care paradigms will be reviewed in this session.

Self-driving cars, remote control of drones, and self-navigating planes are all current realities. However, mapping and ablation of cardiac arrhythmias is a completely human and labor-intensive endeavor, despite many advances over the years. This session will discuss the key barriers and potential solutions that may enable remote control of mapping and ablation as well as semi-autonomous systems for mapping and ablation.

This session will explore signal fidelity and noise reduction in the EP lab, AI-augmented EGM interpretation, regulatory/validation/integration challenges for FDA approval and integration with 3D mapping systems, and clinical research opportunities using AI-driven procedural endpoints.

This session will highlight the challenges, current best practices, and how innovation will impact regulatory science, with a focus on first-in-human device trials. The session will highlight shared and unique challenges in different regions of the world, including Asia, Europe, and North America. Attendees will be armed with a better understanding of the key barriers and facilitators for successful first-in-human trials.

The 2023 HRS/EHRA/LAHRS expert consensus statement on practical management of the remote device clinic reiterates and reinforces the critical necessity to establish and maintain patient connectivity in order to deliver positive patient outcomes via remote monitoring. This session will explore the very real challenges in maintaining connectivity and the ways practitioners address the issue.

This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.

By the time of HRX 2025, pulsed field ablation will have been clinically available in the US for more than a year and a half. While first-gen systems have brought notable changes to EP, these first-generation systems only represent the very beginning of PFA. This session will focus on discussion of the key developments and advances for next generation PFA technologies, including advances in pulse sequences, catheter design, integration with electroanatomic mapping, and patient- and anatomic-specific custom lesion formation.

As healthcare shifts toward proactive interventions, AI holds the promise of detecting heart failure before overt symptoms appear. In this session, experts will discuss how machine learning and big-data analytics can arm clinicians with real-time insights to intervene at the earliest sign of HF decompensation. Attendees will gain an understanding of predictive models, novel monitoring tools, and the challenges involved in implementing such technologies on a broad scale.

This session will explore cutting-edge approaches to patient education, focusing on the integration of digital tools and interactive platforms. Participants will gain insights into the latest best practices for educating patients and healthcare professionals, enhancing engagement, understanding, and overall patient outcomes.

AF management is an essential part of any cardiovascular practice. Today there are more opportunities and technologies to evaluate, follow, and manage AF than ever before. These technologies include next generation implantable monitors, wearables, smartphone app innovations, AI patient navigators, and other patient management tools. This session will explore integrating innovative technologies to optimize patient management at the individual, practice, and population level. The session will explore how these technologies can disrupt traditional care models and provide synergy for more efficient and patient-centered care in the AF clinics of tomorrow.

EP is at the forefront of technological innovation—but it also faces mounting challenges: increasing case complexity, workforce shortages, procedural inefficiencies, and the need for better predictive tools to guide therapy. AI offers the potential to address these headwinds by improving procedural planning, streamlining workflows, optimizing outcomes, and transforming the EP lab into a more intelligent, adaptive environment.

In this dynamic roundtable, thought leaders from across clinical practice, data science, and medtech will explore how AI can be thoughtfully applied to tackle real-world obstacles in EP. Through interactive discussion and illustrative case examples, this session will examine current barriers to adoption, regulatory and ethical considerations, and the importance of data infrastructure to enable AI solutions that are accurate, scalable, and clinically meaningful.

This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.

This session will introduce a new initiative aimed at fostering collaboration among clinical, translational, and basic researchers. As a follow-up to presentations at Heart Rhythm 2025, the roundtable will highlight opportunities for innovation—particularly partnerships with industry—and explore how the Network will support mentorship, multi-center studies, and the development of a robust data warehouse. Discussions will cover data-sharing best practices, priority arrhythmia conditions, and the initiative’s potential to accelerate AI-driven research.

Innovation in cardiology remains a central driving force to better patient care. This session explores how emerging technologies provide both opportunities and challenges to execute.

The advent of multiple sensors in wearables begins to provide clinicians with a treasure trove of data of unknown impact and usefulness. This session will examine tech and the patient experience of employing it.

We will discuss key issues surrounding interoperability and integration, exploring innovative solutions for seamless data flow across multiple monitoring systems. Additionally, we will evaluate the role of AI to support clinical decision-making, enhancing both patient outcomes and operational efficiency. Join us to explore the future of remote monitoring and data management, and how innovations in this field are shaping the future of healthcare

This moderated AbstracX session features presentations from four selected authors, each showcasing innovative research and insights. Join us for a dynamic exchange of ideas and expert discussion.